File contents:
A. List of diagnoses
B. Incidence projections
C. Incidence projections by age group
D. Country-specific parameters
E. Citation

*** A. List of diagnoses ***
List of 48 diagnosis groups defined by the International Classification of Childhood Cancer

File: diagnoses.csv


*** B. Incidence projections ***
Estimated incidence of total and diagnosed cancers 2015-2030 by group and diagnosis

|File             |Contents                    |
|-----------------|----------------------------|
|Inc_Proj_Mean.csv|Projected incidence - mean  |
|Inc_Proj_LB.csv  |Projected incidence - 95% LB|
|Inc_Proj_UB.csv  |Projected incidence - 95% UB|

Column headers

|Column Label     |Description                                             |
|-----------------|--------------------------------------------------------|
|ISOCode          |Grouping or country code (ISO-3)                        |
|Inc_0 to Inc_15  |Total incident cases 2015-2030                          |
|Dx_0 to Dx_15    |Diagnosed cases 2015-2030                               |
|G_0_Inc_0        |Group 1 (Leukemia) total cases in 2015                  |
|...              |...                                                     |
|G_11_Inc_15      |Group 12 (Other) total cases in 2030                    |
|G_0_Dx_0         |Group 1 (Leukemia) diagnosed cases in 2015              |
|...              |...                                                     |
|G_11_Dx_15       |Group 12 (Other) diagnosed cases in 2030                |
|C_0_Inc_0        |Diagnosis 1 (ALL) total cases in 2015                   |
|...              |...                                                     |
|C_47_Inc_15      |Diagnosis 48 (Other unspecified) total cases in 2030    |
|C_0_Dx_0         |Diagnosis 1 (ALL) diagnosed cases in 2015               |
|...              |...                                                     |
|C_47_Dx_15       |Diagnosis 48 (Other unspecified) diagnosed cases in 2030|


*** C. Incidence projections by age group ***
Estimated incidence of total and diagnosed cancers 2015-2030 by age group (<1, 1-4, 5-9, 10-14) and diagnosis

NOTE: These age group-specific projections were estimated in a new set of simulations.
Due to stochastic uncertainty (i.e. random noise), the sum of the age group means does not exactly equal the overall incidence projections (above).
They will be very close however - typically less than 1% difference.


|File                 |Contents                                 |
|---------------------|-----------------------------------------|
|Inc_Proj_Age_Mean.csv|Projected incidence by age group - mean  |
|Inc_Proj_Age_LB.csv  |Projected incidence by age group - 95% LB|
|Inc_Proj_Age_UB.csv  |Projected incidence by age group - 95% UB|

Column headers

|Column Label                |Description                                                               |
|----------------------------|--------------------------------------------------------------------------|
|ISOCode                     |Grouping or country code (ISO-3)                                          |
|Age_0_Inc_0 to Age_0_Inc_15 |Total incident cases 2015-2030, age group: <1                             |
|Age_0_Dx_0 to Age_0_Dx_15   |Diagnosed cases 2015-2030, age group: <1                                  |
|Age_0_G_0_Inc_0             |Group 1 (Leukemia) total cases in 2015, age group: <1                     |
|...                         |...                                                                       |
|Age_0_G_11_Inc_15           |Group 12 (Other) total cases in 2030, age group: <1                       |
|Age_0_G_0_Dx_0              |Group 1 (Leukemia) diagnosed cases in 2015, age group: <1                 |
|...                         |...                                                                       |
|Age_0_G_11_Dx_15            |Group 12 (Other) diagnosed cases in 2030, age group: <1                   |
|Age_0_C_0_Inc_0             |Diagnosis 1 (ALL) total cases in 2015, age group: <1                      |
|...                         |...                                                                       |
|Age_0_C_47_Inc_15           |Diagnosis 48 (Other unspecified) total cases in 2030, age group: <1       |
|Age_0_C_0_Dx_0              |Diagnosis 1 (ALL) diagnosed cases in 2015, age group: <1                  |
|...                         |...                                                                       |
|Age_0_C_47_Dx_15            |Diagnosis 48 (Other unspecified) diagnosed cases in 2030, age group: <1   |
|Age_1_Inc_0 to Age_1_Inc_15 |Total incident cases 2015-2030, age group: 1-4                            |
|...                         |...                                                                       |
|Age_2_Inc_0 to Age_2_Inc_15 |Total incident cases 2015-2030, age group: 5-9                            |
|...                         |...                                                                       |
|Age_3_Inc_0 to Age_3_Inc_15 |Total incident cases 2015-2030, age group: 10-14                          |
|...                         |...                                                                       |
|Age_3_C_47_Dx_15            |Diagnosis 48 (Other unspecified) diagnosed cases in 2030, age group: 10-14|


*** D. Country-specific parameters ***
Summary of calibrated model parameters (access/referral) for each country

|File                    |Contents                  |
|------------------------|--------------------------|
|countryParams_Mean.csv  |Parameter values - mean   |
|countryParams_LB.csv    |Parameter values - 95% LB |
|countryParams_UB.csv    |Parameter values - 95% UB |

Column headers

|Column Label          |Description                                                |
|----------------------|-----------------------------------------------------------|
|ISOCode               |Country code                                               |
|Access_R              |Probability of access to primary care - Rural              |
|Access_U              |Probability of access to primary care - Urban              |
|Referral_R            |Probability of referral - Rural                            |
|Referral_U            |Probability of referral - Urban                            |


*** E. Citation ***
Ward ZJ, Yeh JM, Bhakta N, Frazier AL, Atun R. 
Estimating the total incidence of global childhood cancer: a simulation-based analysis. 
Lancet Oncol 2019; 20(4): 483-493.
